Core Facilities

Core Facilities

CAS research often relies on the use of shared instrumentation for routine and advanced analyses. CAS Core Facilities are designed to help researchers improve the health and wellbeing of people, create healthy and sustainable communities, and explore ways to advance healthy communities through novel and innovative research.

Electron Microscope Core Facility

The Electron Microscope Core Facility provides microscope services to universities, industry, and commercial labs to include Transmission and Scanning Electron Microscopy, Transmitted and Fluorescent Light Microscopy, Specimen Preparation, and Instrument Training in TEM, SEM, Light Microscopy, and Consulting.

Nuclear Magnetic Resonance Core Facility

The NMR Core Facility houses a range of nuclear magnetic resonance instrumentation, including one of Florida's highest field strength NMRs (800 MHz). Expertise and facilities are available for academic, government, and commercial structural studies, metabolomics, and materials research. One specialty involves measuring the magnetic properties of atomic nuclei, which makes up the molecules that can become future pharmaceutical drugs.

Cell Biology, Microbiology, and Molecular Biology Core Facility

The CMMB Core Facility offers a wide range of resources that include products, education, services, and support that assist scientists, industry, and students in solving research problems.

Chemical Purification, Analysis, and Screening Core Facility

The CPAS Core Facility offers its expertise in chromatographic separation and purification (MPLC, HPLC, UHPLC), mass spectrometry detection, and identification and quantification (LC-MS SQ, LC-MS QqQ, LC-MS ToF, LC-MS QToF, GC-MSD, GC-MS QToF). Services also include Circular Dichroism, general spectroscopic characterization (UV, FTIR), lyophilization (benchtop and general purpose freeze-dryer), synthesis (microwave reactor), ADME screening (PAMPA and drug solubility), and high-throughput screening development capability (liquid handling robot and multimode plate reader). The facility provides research lab training and assistance so users can operate any instruments necessary to successfully accomplish their research projects.

Center for Geochemical Analysis

The CGA Core Facility specializes in low-level trace element analysis. This core employs inductively coupled plasma (ICP) spectrometers with coupled laser and HPLC to provide analyses on water, soil, chemicals, biologic material, and rocks for the greater USF community, national, and global research institutions, as well as local and federal government agencies. This core also specializes in the determination of trace metals in a variety of materials including water samples, environmental samples (e.g., soil, sludge), and most rock types. This lab provides analysis to the public, research institutions, government agencies, and universities.

Stable Isotope Lab

The Stable Isotope Lab offers analyses of both organic and inorganic samples (including C, H, O, N, and S elements) to researchers in geology, anthropology, biology, geography, and more.

Solid State Structure Core Facility

The Solid State Structure Core Facility provides analyses of sample materials.

Proteomics Core Facility

The Proteomics Core Facility provides expertise in biological mass spectrometry as it relates to project development, experimental design, sample processing, and data analysis for proteomics studies. This core facility also provides training in sample processing and database searching for graduate students and post-doctoral scholars.

The Proteomics Core maintains a hybrid quadrupole-orbitrap mass spectrometer (Q Exactive Plus, Thermo Scientific) equipped with a Thermo Ultimate 3000 UHPLC system. The Q Executive Plus is ideal for proteomics applications such as large-scale protein identification experiments from complex biological samples including relative quantitation, as well as routine protein identification from immunoprecipitation experiments and various post-translational modification (PTM) analyses. This core is also proficient in a number of sample processing workflows and has broad experience with a variety of sample types. Comprehensive data analysis is provided, primarily relying on MaxQuant and Perseus software packages. The bioinformatic analysis is also available using software Ingenuity Pathway Analysis (IPA).

Access 3D Lab

The Access 3D Lab incubates and supports transformative research and teaching in STEM disciplines, the arts, and the humanities. 3D scanning presents countless opportunities for analytical and creative projects, such as virtual museum creation, machine parts design and phototyping, digital sculpting, and forensic analysis. As a shared user facility, the lab is open to USF faculty and students from all disciplines. We provide access to high-end 3D scanners, data processing software, training and workshops, project consultations, and a collaborative workspace. Our instrumentation consists of handheld structured light scanners, a FARO arm scanner, terrestrial laser scanners, a photogrammetry studio, a drone, 13 computer workstations, and a 3D-enabled 24-seat classroom with a Promethean ActivPanel interactive display. Our goal is to use these resources to enhance learning, faculty research, and community engagement at USF and beyond.