CAS research often relies on the use of shared instrumentation for routine and advanced analyses. CAS Core Facilities are designed to help researchers improve the health and wellbeing of people, create healthy and sustainable communities, and explore ways to advance healthy communities through novel and innovative research.
The Electron Microscopy Core Facility provides microscope services to university, industry, and commercial labs that include Transmission and Scanning Electron Microscopy, Transmitted and Fluorescent Light Microscopy, Specimen Preparation, and Instrument Training in TEM, SEM, Light Microscopy, and Consulting.
The Nuclear Magnetic Resonance Core Facility houses a range of nuclear magnetic resonance instrumentation, including one of Florida's highest field strength NMRs (800 MHz). Expertise and facilities are available for academic, government, and commercial studies in structural, metabolomics, and materials research. We specialize in measuring the magnetic properties of atomic nuclei, which make up the molecules that can become future pharmaceutical drugs.
The Chemical Purification, Analysis, and Screening Core Facility offers expertise in chromatographic separation and purification (MPLC, HPLC, UHPLC); and mass spectrometry detection, identification, and quantification (LC-MS SQ, LC-MS QqQ, LC-MS ToF, LC-MS QToF, GC-MSD, GC-MS QToF). Services include circular dichroism, general spectroscopic characterization (UV, FTIR), lyophilization (benchtop and general purpose freeze-dryer), synthesis (microwave reactor), ADME screening (PAMPA and drug solubility), and high-throughput screening development capability (liquid handling robot and multimode plate reader). This facility provides research lab training and assistance to users so they can operate any instruments necessary to successfully accomplishing their research goals.
The Center for Geochemical Analysis specializes in the determination of trace metals in a variety of materials including water samples, environmental samples (e.g., soil, sludge), and most rock types. The CGA employs two Inductively Coupled Plasma (ICP) Mass Spectrometers, an ICP Optical Emission Spectrometer, and two specialized Ion Chromatography Systems that work with the ICP-MS and independently for the determination of speciation for both metals and anions. Combined, the CGA provides analyses of low abundance elements in water, soils, chemicals, biologic materials, and rocks for the greater USF community, national and global research institutions, and federal and local government agencies.
The Stable Isotope Lab offers analyses of both organic and inorganic samples (including C, H, O, N, and S elements) to researchers from the geosciences, anthropology, biology, and more.
The X-Ray Diffraction and Solid-State Characterization Lab provides access to instrumentation and services needed to characterize crystalline solid-state samples. The lab specializes in crystallography, single crystal x-ray diffraction, and powder x-ray diffraction. We use x-ray diffraction methods to solve structures of single crystals and to identify and characterize crystalline powder samples. The lab also provides access to TGA, DSC, FT-IR, and UV-VIS instruments and is extensively used by synthetic and materials scientists working at USF and other academic institutions and commercial entities.
The Proteomics Core Facility provides expertise in biological mass spectrometry for large-scale protein identification and characterization, as well as quantitative proteomics-based workflows. The facility is equipped with high-performance mass spectrometers with electrospray ionization sources coupled to nano-flow liquid chromatographs - ideal for proteomics applications.
The Access 3D Lab incubates and supports transformative research and teaching in STEM disciplines, the arts, and the humanities. 3D scanning presents countless opportunities for analytical and creative projects such as virtual museum creation, machine parts design and phototyping, digital sculpting, and forensic analysis. As a shared user facility, the lab is open to USF faculty and students from all disciplines. We provide access to high-end 3D scanners, data processing software, training and workshops, project consultations, and a collaborative workspace.