Core Facilities
Chemical Purification Analysis and Screening core facility (CPAS)
Laurent Calcul, Ph.D. (Director)
calcul@usf.edu (preferred method)
Phone NES 406/IDRB 318: (813) 974-6031
Fax: (813) 974-3203
Need a Reservation? Please Check the Instrument availability below:
- at CPAS NES 406
- at CPAS IDRB 318
- for the MALDI TOF/TOF at IDRB 318
OVERVIEW
CPAS offers its expertise in chromatographic separation and purification (MPLC, HPLC, UHPLC), mass spectrometry detection, identification and quantification (LC-MS SQ, LC-MS QqQ, LC-MS ToF, LC-MS QToF, GC-MSD and GC-MS QToF and MALDI TOF). The services also include Circular Dichroism, general spectroscopic characterization (UV, FTIR), lyophilization (benchtop and general purpose freeze-dryer), synthesis (microwave reactor), ADME screening (Parallel Artificial Membrane Permeability [PAMPA] and drug solubility evaluation), and high-throughput screening development capability (liquid handling robot and multimode plate reader). Instruments at CPAS are available 24/7 upon reservation in self-service for users who completed the training.
- Contact & Billing
- Usage Fees
- Information Poster
- Mass Spectrometry Analysis Form
- Acknowledgement Co-Authorship
USF CPAS EQUIPMENT AND SERVICES (NES 406 and IDRB 318)
CPAS, NES 406

Agilent GC-MSD 5977B
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Dionex ultimate 3000 UHPLC DAD

AVIV Model 215 Circular Dichroism Spectrometer
CPAS, IDRB 318
- Agilent 7890A GC-MS QToF 7200
- Agilent 1200 LC-MS TOF 6230
- Agilent 1260 Preparative HPLC-DAD-MS SQ 6120
- Teledyne-Isco MPLC (UV) and Shimadzu HPLC (UV, ELSD, EID)
- Parallel Artificial membrane Permeability Assay (GIT, BBB, Skin PAMPA)
- Solubility evaluation
- High-throughput Screening Capabilities
- Anton Paar Monowave Reactor 300
- Agilent Cary 60 UV-Vis Spectrophotometer and FTIR 630 Spectrometer
- Freeze Drying and Concentration
- Innovatice Technologies Pure Solv Micro solvent purification system for anhydrous solvent preparation

Bruker UltraFleXtreme MALDI- TOF/TOF
- Smartbeam II, 2 GHz for MS and 1 GHz for MS/MS
- FlashDetector™ with 5 GS/s 10 bit digitizer for enhanced dynamic range
- Resolution > 45,000
- Analytes: - Protein, peptide, lipids, natural products and polymer
- Software: - FlexControl, FlexAnalysis, FlexImaging
- Supporting Software: Biotools, Polytools, SCiLS Lab