Dr. Andrii Monastyrskyi
EXTERNAL GRADUATE AFFILIATE FACULTY (MOFFITT CANCER CENTER)
- Ph.D., University of South Florida
Advisor: Roman Manetsch
- NIH NRSA Postdoctoral Fellow, The Scripps Research Institute
Advisor: William Roush
Our laboratory uses the tools of synthetic organic chemistry, medicinal chemistry, and chemical biology to further develop small molecules for studying and modulating therapeutically relevant cancer targets. One aspect of current work focuses on the development of IND safety assessment candidates that inhibit the transcriptional kinases CDK12 and CDK13, the Wnt/beta-catenin regulators CK1d and CK1e, and the autophagy kinase ULK1. Further, developmental projects in the laboratory include campaigns to develop small molecules that disrupt key protein-protein interactions (e.g., those of Myc and Max) and RNA biogenesis
Now Recruiting! We are currently accepting graduate students from the Department of Chemistry. Students will receive a thorough training in synthetic organic chemistry, medicinal chemistry, rational drug design, and translational research in cancer drug discovery.